› 1sda

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF PEROXYNITRITE-MODIFIED BOVINE CU,ZN SUPEROXIDE DISMUTASE

Released:
DOI: 10.2210/pdb1sda/pdb
PDB entry 1sda coloured by chain, front view.
PDB entry 1sda coloured by chain, side view.
PDB entry 1sda coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of peroxynitrite-modified bovine Cu,Zn superoxide dismutase.
Smith CD, Carson M, van der Woerd M, Chen J, Ischiropoulos H, Beckman JS
Arch Biochem Biophys 299 350-5 (1992)
PMID: 1444476

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chains: B, G, O, Y
Molecule details ›
Chains: B, G, O, Y
Length: 152 amino acids
Theoretical weight: 15.64 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00442 (Residues: 2-152; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

2 bound ligands:
Ligand CU 4 x CU
Ligand ZN 4 x ZN
1 modified residue:
Ligand NIY 4 x NIY

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 93.65Å b: 90.33Å c: 71.65Å
α: 90° β: 95.1° γ: 90°
R-values:
R R work R free
0.187 0.187 not available
Expression system: Not provided

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Citations

9 review citations

Nitric oxide and peroxynitrite in health and disease.
Pacher et al. (2007)
8 more