1sfu

X-ray diffraction
2Å resolution

Crystal structure of the viral Zalpha domain bound to left-handed Z-DNA

Released:

Function and Biology Details

Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-114591 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Protein E3 homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 75 amino acids
Theoretical weight: 8.72 KDa
Source organism: Yaba-like disease virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9DHS8 (Residues: 1-75; Coverage: 41%)
Gene name: 34L
Sequence domains: Adenosine deaminase z-alpha domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
5'-D(*T*CP*GP*CP*GP*CP*G)-3' Chains: C, D
Molecule details ›
Chains: C, D
Length: 7 nucleotides
Theoretical weight: 2.11 KDa
Source organism: Yaba-like disease virus
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P21212
Unit cell:
a: 51.203Å b: 92.452Å c: 48.012Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.238 0.27
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided