› 1sfw

Solution NMR

PORCINE PANCREAS PHOSPHOLIPASE A2, NMR, 18 STRUCTURES

Released:
DOI: 10.2210/pdb1sfw/pdb
PDB entry 1sfw coloured by chain, ensemble of 18 models, front view.
PDB entry 1sfw coloured by chain, ensemble of 18 models, side view.
PDB entry 1sfw coloured by chain, ensemble of 18 models, top view.
Source organism: Sus scrofa
Primary publication:
Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor.
van den Berg B, Tessari M, Boelens R, Dijkman R, Kaptein R, de Haas GH, Verheij HM
J Biomol NMR 5 110-21 (1995)
PMID: 7703697

Function and Biology Details

Reaction catalysed: 
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132748 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phospholipase A2, major isoenzyme Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 14.01 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P00592 (Residues: 23-146; Coverage: 95%)
Gene name: PLA2G1B
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The interfacial binding surface of phospholipase A2s.
Winget et al. (2006)
3 more

1 mention without citation

The FEATURE framework for protein function annotation: modeling new functions, improving performance, and extending to novel applications.
Halperin et al. (2008)