› 1sgs

X-ray diffraction
1.6Å resolution

Crystal structure of a free kB DNA

Released:
DOI: 10.2210/pdb1sgs/pdb
PDB entry 1sgs coloured by chain, front view.
PDB entry 1sgs coloured by chain, side view.
PDB entry 1sgs coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB.
Huang DB, Phelps CB, Fusco AJ, Ghosh G
J Mol Biol 346 147-60 (2005)
PMID: 15663934

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114592 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
kB DNA Chain: A
Molecule details ›
Chain: A
Length: 17 nucleotides
Theoretical weight: 5.19 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand CA 6 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: R32
Unit cell:
a: 38.916Å b: 38.916Å c: 158.91Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.207 0.218
Expression system: Not provided

Quick links

Citations

5 review citations

Origins of specificity in protein-DNA recognition.
Rohs et al. (2010)
4 more

3 mentions without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)
2 more