› 1soc

Solution NMR

NMR STUDY OF THE BACKBONE CONFORMATIONAL EQUILIBRIA OF SANDOSTATIN, MINIMIZED AVERAGE BETA-SHEET STRUCTURE

Released:
DOI: 10.2210/pdb1soc/pdb
PDB entry 1soc coloured by chain, front view.
PDB entry 1soc coloured by chain, side view.
PDB entry 1soc coloured by chain, top view.
Source organism: Unidentified
Primary publication:
Multiconformational NMR analysis of sandostatin (octreotide): equilibrium between beta-sheet and partially helical structures.
Melacini G, Zhu Q, Goodman M
Biochemistry 36 1233-41 (1997)
PMID: 9063871

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162452 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SANDOSTATIN Chain: A
Molecule details ›
Chain: A
Length: 8 amino acids
Theoretical weight: 1.02 KDa
Source organism: Unidentified
Expression system: Not provided

Ligands and Environments

No bound ligands
3 modified residues:
Ligand DPN 1 x DPN
Ligand DTR 1 x DTR
Ligand THO 1 x THO

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

6 review citations

Constraining cyclic peptides to mimic protein structure motifs.
Hill et al. (2014)
5 more

6 mentions without citation

Early engineering approaches to improve peptide developability and manufacturability.
Furman et al. (2015)
5 more