› 1sov

X-ray diffraction
1.9Å resolution

Toxoplasma gondii bradyzoite-specific LDH (LDH2) apo form

Released:
DOI: 10.2210/pdb1sov/pdb
PDB entry 1sov coloured by chain, front view.
PDB entry 1sov coloured by chain, side view.
PDB entry 1sov coloured by chain, top view.
Source organism: Toxoplasma gondii
Entry authors: Kavanagh KL, Wilson DK

Function and Biology Details

Reaction catalysed: 
(S)-lactate + NAD(+) = pyruvate + NADH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173285 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L-lactate dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 328 amino acids
Theoretical weight: 35.53 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q27797 (Residues: 1-326; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: I4122
Unit cell:
a: 142.939Å b: 142.939Å c: 164.518Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.173 0.201
Expression system: Escherichia coli

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