› 1soy

Solution NMR

Solution structure of the bacterial frataxin orthologue, CyaY

Released:
DOI: 10.2210/pdb1soy/pdb
PDB entry 1soy coloured by chain, ensemble of 20 models, front view.
PDB entry 1soy coloured by chain, ensemble of 20 models, side view.
PDB entry 1soy coloured by chain, ensemble of 20 models, top view.
Source organism: Escherichia coli
Primary publication:
Solution structure of the bacterial frataxin ortholog, CyaY: mapping the iron binding sites.
Nair M, Adinolfi S, Pastore C, Kelly G, Temussi P, Pastore A
Structure 12 2037-48 (2004)
PMID: 15530368

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151086 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Iron-sulfur cluster assembly protein CyaY Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.37 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P27838 (Residues: 1-106; Coverage: 100%)
Gene names: JW3779, b3807, cyaY
Sequence domains: Frataxin-like domain
Structure domains: Frataxin/CyaY

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

23 review citations

Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms.
Lill et al. (2006)
22 more

8 mentions without citation

Friedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.
Santos et al. (2010)
7 more