› 1sq3

X-ray diffraction
2.7Å resolution

Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus.

Released:
DOI: 10.2210/pdb1sq3/pdb
PDB entry 1sq3 coloured by chain, front view.
PDB entry 1sq3 coloured by chain, side view.
PDB entry 1sq3 coloured by chain, top view.
Source organism: Archaeoglobus fulgidus DSM 4304
Primary publication:
Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Johnson E, Cascio D, Sawaya MR, Gingery M, Schröder I
Structure 13 637-48 (2005)
PMID: 15837202

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128125 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin-like diiron domain-containing protein Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 173 amino acids
Theoretical weight: 20.76 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
  • Canonical: O29424 (Residues: 1-173; Coverage: 100%)
Gene name: AF_0834
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

1 bound ligand:
Ligand FE 36 x FE
1 modified residue:
Ligand MSE 108 x MSE

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 184.502Å b: 190.243Å c: 179.407Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.218
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Engineering protein nanocages as carriers for biomedical applications.
Bhaskar et al. (2017)
9 more

6 mentions without citation

Crystal structure of the ferritin from the hyperthermophilic archaeal anaerobe Pyrococcus furiosus.
Tatur et al. (2007)
5 more