› 1su0

X-ray diffraction
2.3Å resolution

Crystal structure of a hypothetical protein at 2.3 A resolution

Released:
DOI: 10.2210/pdb1su0/pdb
PDB entry 1su0 coloured by chain, front view.
PDB entry 1su0 coloured by chain, side view.
PDB entry 1su0 coloured by chain, top view.
Source organism: Streptococcus pyogenes
Primary publication:
Structural characterization of an iron-sulfur cluster assembly protein IscU in a zinc-bound form.
Liu J, Oganesyan N, Shin DH, Jancarik J, Yokota H, Kim R, Kim SH
Proteins 59 875-81 (2005)
PMID: 15815978

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189454 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Iron-sulfur cluster assembly scaffold protein IscU Chain: B
Molecule details ›
Chain: B
Length: 159 amino acids
Theoretical weight: 17.16 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9A1G2 (Residues: 1-159; Coverage: 100%)
Gene names: M5005_Spy0245, SPy_0289, iscU, nifU
Sequence domains: NifU-like N terminal domain
Structure domains: Sufe protein. Chain: A

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: I422
Unit cell:
a: 72.014Å b: 72.014Å c: 112.713Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.22 0.256
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Function and biogenesis of iron-sulphur proteins.
Lill R. (2009)
4 more

12 mentions without citation

Tangled web of interactions among proteins involved in iron-sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies.
Kim et al. (2015)
11 more