Function and Biology Details
Reaction catalysed:
(S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H(+)
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
- Cytochrome b5-like heme/steroid binding domain
- Cytochrome b5-like heme/steroid binding domain superfamily
- FMN-dependent alpha-hydroxy acid dehydrogenase, active site
- FMN-dependent dehydrogenase
- L-mandelate/L-lactate dehydrogenase, FMN-binding domain
- FMN hydroxy acid dehydrogenase domain
- Aldolase-type TIM barrel
- Cytochrome b5, heme-binding site
Structure domain:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
L-lactate dehydrogenase (cytochrome) (preferred)
PDBe Complex ID:
PDB-CPX-132308 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L-lactate dehydrogenase (cytochrome)
Molecule details ›
Chains: A, B
Length: 511 amino acids
Theoretical weight: 56.62 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Aldolase class I
Length: 511 amino acids
Theoretical weight: 56.62 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
- Canonical:
P00175 (Residues: 81-591; Coverage: 87%)
Sequence domains:
Structure domains: Aldolase class I
