› 1t2j

X-ray diffraction
1.5Å resolution

Crystal structure of a Human VH domain

Released:
DOI: 10.2210/pdb1t2j/pdb
PDB entry 1t2j coloured by chain, front view.
PDB entry 1t2j coloured by chain, side view.
PDB entry 1t2j coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Gaur RK, Fischer R, Hoffmann KMV

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190773 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 12.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HCC1 (Residues: 1-112; Coverage: 100%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: C2
Unit cell:
a: 71.336Å b: 37.965Å c: 37.187Å
α: 90° β: 109.67° γ: 90°
R-values:
R R work R free
0.176 0.158 0.197
Expression system: Escherichia coli

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