› 1t54

Solution NMR

Antibiotic Activity and Structural Analysis of a Scorpion-derived Antimicrobial peptide IsCT and Its Analogs

Released:
DOI: 10.2210/pdb1t54/pdb
PDB entry 1t54 coloured by chain, ensemble of 20 models, front view.
PDB entry 1t54 coloured by chain, ensemble of 20 models, side view.
PDB entry 1t54 coloured by chain, ensemble of 20 models, top view.
Source organism: Opisthacanthus madagascariensis
Primary publication:
Antibiotic activity and structural analysis of the scorpion-derived antimicrobial peptide IsCT and its analogs.
Lee K, Shin SY, Kim K, Lim SS, Hahm KS, Kim Y
Biochem Biophys Res Commun 323 712-9 (2004)
PMID: 15369808

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185318 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxic linear peptide IsCT Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.39 KDa
Source organism: Opisthacanthus madagascariensis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8MMJ7 (Residues: 24-36; Coverage: 29%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing
Expression system: Escherichia coli

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Citations

9 review citations

Antimicrobial peptides from scorpion venoms.
Harrison et al. (2014)
8 more