1t5o

X-ray diffraction
1.9Å resolution

Crystal structure of the translation initiation factor eIF-2B, subunit delta, from A. fulgidus

Released:
Entry authors: Malashkevich VN, Almo SC, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed:
S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-128181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative methylthioribose-1-phosphate isomerase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 351 amino acids
Theoretical weight: 39.04 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
UniProt:
  • Canonical: O29877 (Residues: 2-339; Coverage: 100%)
Gene name: AF_0370
Sequence domains: Initiation factor 2 subunit family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300, NSLS BEAMLINE X9A
Spacegroup: P212121
Unit cell:
a: 105.575Å b: 110.202Å c: 141.498Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.246