› 1tf1

X-ray diffraction
1.8Å resolution

Crystal Structure of the E. coli Glyoxylate Regulatory Protein Ligand Binding Domain

Released:
DOI: 10.2210/pdb1tf1/pdb
PDB entry 1tf1 coloured by chain, front view.
PDB entry 1tf1 coloured by chain, side view.
PDB entry 1tf1 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Structural and biochemical study of effector molecule recognition by the E.coli glyoxylate and allantoin utilization regulatory protein AllR.
Walker JR, Altamentova S, Ezersky A, Lorca G, Skarina T, Kudritska M, Ball LJ, Bochkarev A, Savchenko A
J Mol Biol 358 810-28 (2006)
PMID: 16546208

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142286 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional repressor AllR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 198 amino acids
Theoretical weight: 21.47 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ACN4 (Residues: 97-271; Coverage: 65%)
Gene names: JW0494, allR, b0506, glxA3, ybbU
Sequence domains: Bacterial transcriptional regulator
Structure domains: Beta-Lactamase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: C2221
Unit cell:
a: 92.796Å b: 97.538Å c: 144.488Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.257
Expression system: Escherichia coli

Quick links

Citations

12 citation in other articles

Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators.
Lu et al. (2010)
11 more

1 mention without citation

The IclR family of transcriptional activators and repressors can be defined by a single profile.
Krell et al. (2006)