› 1tm6

Solution NMR

NMR Structure of the Free Zinc Binding C-terminal Domain of SecA

Released:
DOI: 10.2210/pdb1tm6/pdb
PDB entry 1tm6 coloured by chain, ensemble of 20 models, front view.
PDB entry 1tm6 coloured by chain, ensemble of 20 models, side view.
PDB entry 1tm6 coloured by chain, ensemble of 20 models, top view.
Source organism: Escherichia coli
Primary publication:
NMR structure of the C-terminal domain of SecA in the free state.
Matousek WM, Alexandrescu AT
Biochim Biophys Acta 1702 163-71 (2004)
PMID: 15488768

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + cellular protein(Side 1) = ADP + phosphate + cellular protein(Side 2)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145293 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein translocase subunit SecA Chain: A
Molecule details ›
Chain: A
Length: 22 amino acids
Theoretical weight: 2.44 KDa
Source organism: Escherichia coli
UniProt:
  • Canonical: P10408 (Residues: 880-901; Coverage: 2%)
Gene names: JW0096, azi, b0098, pea, prlD, secA
Sequence domains: SEC-C motif

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: standard x-plor protocol; 1. distance geometry sub-embed 2. distance geometry full embed 3. simulated annealing 4. simulated annealing refine

Quick links

Citations

7 review citations

Sec- and Tat-mediated protein secretion across the bacterial cytoplasmic membrane--distinct translocases and mechanisms.
Natale et al. (2008)
6 more

1 mention without citation

Iron is a ligand of SecA-like metal-binding domains in vivo.
Cranford-Smith et al. (2020)