› 1tob

Solution NMR

SACCHARIDE-RNA RECOGNITION IN AN AMINOGLYCOSIDE ANTIBIOTIC-RNA APTAMER COMPLEX, NMR, 7 STRUCTURES

Released:
DOI: 10.2210/pdb1tob/pdb
PDB entry 1tob coloured by chain, ensemble of 7 models, front view.
PDB entry 1tob coloured by chain, ensemble of 7 models, side view.
PDB entry 1tob coloured by chain, ensemble of 7 models, top view.
Source organism: synthetic construct
Primary publication:
Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex.
Jiang L, Suri AK, Fiala R, Patel DJ
Chem Biol 4 35-50 (1997)
PMID: 9070426

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196221 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-R(GGCACGAGGUUUAGCUACACUCGUGCC)-3') Chain: A
Molecule details ›
Chain: A
Length: 27 nucleotides
Theoretical weight: 8.64 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand TOA 1 x TOA
Ligand TOC 1 x TOC
Ligand TOB 1 x TOB
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

17 review citations

In vitro selection of functional nucleic acids.
Wilson et al. (1999)
16 more

4 mentions without citation

Selection and Biosensor Application of Aptamers for Small Molecules.
Pfeiffer et al. (2016)
3 more