› 1ts4

X-ray diffraction
3.4Å resolution

Q139K MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS

Released:
DOI: 10.2210/pdb1ts4/pdb
PDB entry 1ts4 coloured by chain, front view.
PDB entry 1ts4 coloured by chain, side view.
PDB entry 1ts4 coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Earhart CA, Mitchell DT, Murray DL, Pinheiro DM, Matsumura M, Schlievert PM, Ohlendorf DH
Biochemistry 37 7194-202 (1998)
PMID: 9585531

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139296 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxic shock syndrome toxin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 194 amino acids
Theoretical weight: 22.1 KDa
Source organism: Staphylococcus aureus
Expression system: Staphylococcus aureus
UniProt:
  • Canonical: P06886 (Residues: 41-234; Coverage: 100%)
Gene name: tst
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: R32
Unit cell:
a: 152.35Å b: 152.35Å c: 142.31Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.21 0.287
Expression system: Staphylococcus aureus

Quick links

Citations

2 review citations

Exotoxins of Staphylococcus aureus.
Dinges et al. (2000)
1 more