› 1ttx

Solution NMR

Solution Structure of human beta parvalbumin (oncomodulin) refined with a paramagnetism based strategy

Released:
DOI: 10.2210/pdb1ttx/pdb
PDB entry 1ttx coloured by chain, ensemble of 20 models, front view.
PDB entry 1ttx coloured by chain, ensemble of 20 models, side view.
PDB entry 1ttx coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of human beta-parvalbumin and structural comparison with its paralog alpha-parvalbumin and with their rat orthologs.
Babini E, Bertini I, Capozzi F, Del Bianco C, Hollender D, Kiss T, Luchinat C, Quattrone A
Biochemistry 43 16076-85 (2004)
PMID: 15610002

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143220 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oncomodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CE72 (Residues: 1-109; Coverage: 100%)
Gene names: OCM, OCM1, OCMN
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing torsion angle dynamics; pseudocontact shifts residual dipolar couplings;
Expression system: Escherichia coli

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Citations

4 review citations

Cytosolic Ca2+ buffers.
Schwaller B. (2010)
3 more

4 mentions without citation

Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Xia et al. (2021)
3 more