› 1tty

Solution NMR

Solution structure of sigma A region 4 from Thermotoga maritima

Released:
DOI: 10.2210/pdb1tty/pdb
PDB entry 1tty coloured by chain, ensemble of 22 models, front view.
PDB entry 1tty coloured by chain, ensemble of 22 models, side view.
PDB entry 1tty coloured by chain, ensemble of 22 models, top view.
Source organism: Thermotoga maritima
Primary publication:
T4 AsiA blocks DNA recognition by remodeling sigma70 region 4.
Lambert LJ, Wei Y, Schirf V, Demeler B, Werner MH
EMBO J 23 2952-62 (2004)
PMID: 15257291

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160216 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA polymerase sigma factor SigA Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 10.38 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: P77994 (Residues: 313-399; Coverage: 22%)
Gene names: TM_1451, rpoD, sigA
Sequence domains: Sigma-70, region 4
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing in torsion angle space
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Advances in bacterial promoter recognition and its control by factors that do not bind DNA.
Haugen et al. (2008)
11 more

4 mentions without citation

Structural biology of bacterial RNA polymerase.
Murakami KS. (2015)
3 more