› 1u2r

X-ray diffraction
2.6Å resolution

Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae

Released:
DOI: 10.2210/pdb1u2r/pdb
PDB entry 1u2r coloured by chain, front view.
PDB entry 1u2r coloured by chain, side view.
PDB entry 1u2r coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of ADP-ribosylated ribosomal translocase from Saccharomyces cerevisiae.
Jørgensen R, Yates SP, Teal DJ, Nilsson J, Prentice GA, Merrill AR, Andersen GR
J Biol Chem 279 45919-25 (2004)
PMID: 15316019

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152261 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

4 bound ligands:
Ligand MG 1 x MG
Ligand APR 1 x APR
Ligand SO1 1 x SO1
Ligand GDP 1 x GDP
1 modified residue:
Ligand DDE 1 x DDE

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P21212
Unit cell:
a: 119.725Å b: 151.002Å c: 65.172Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.227 0.262

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Citations

9 review citations

A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer.
Weldon et al. (2011)
8 more

4 mentions without citation

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Taylor et al. (2007)
3 more