› 1u3d

X-ray diffraction
2.45Å resolution

Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana with AMPPNP bound

Released:
DOI: 10.2210/pdb1u3d/pdb
PDB entry 1u3d coloured by chain, front view.
PDB entry 1u3d coloured by chain, side view.
PDB entry 1u3d coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Brautigam CA, Smith BS, Ma Z, Palnitkar M, Tomchick DR, Machius M, Deisenhofer J
Proc Natl Acad Sci U S A 101 12142-7 (2004)
PMID: 15299148

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174985 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cryptochrome-1 Chain: A
Molecule details ›
Chain: A
Length: 509 amino acids
Theoretical weight: 57.6 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q43125 (Residues: 1-509; Coverage: 75%)
Gene names: At4g08920, BLU1, CRY1, HY4, T3H13.14, T3H13.5
Sequence domains:
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand MG 4 x MG
Ligand CL 1 x CL
Ligand FAD 1 x FAD
Ligand ANP 1 x ANP
Ligand NDS 1 x NDS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6322
Unit cell:
a: 169.213Å b: 169.213Å c: 104.521Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.204 0.253
Expression system: Escherichia coli

Quick links

Citations

44 review citations

The cryptochromes: blue light photoreceptors in plants and animals.
Chaves et al. (2011)
43 more

20 mentions without citation

Optogenetic Immunomodulation: Shedding Light on Antitumor Immunity.
Tan et al. (2017)
19 more