1u4s

X-ray diffraction
2Å resolution

Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedisulphonic acid

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-173280 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L-lactate dehydrogenase Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 34.85 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q27743 (Residues: 2-316; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: I222
Unit cell:
a: 80.094Å b: 86.096Å c: 91.327Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.138 0.136 0.188
Expression system: Escherichia coli