› 1u5m

Solution NMR

Structure of a Chordin-like Cysteine-rich Repeat (VWC module) from Collagen IIA

Released:
DOI: 10.2210/pdb1u5m/pdb
PDB entry 1u5m coloured by chain, ensemble of 20 models, front view.
PDB entry 1u5m coloured by chain, ensemble of 20 models, side view.
PDB entry 1u5m coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and dynamics of a prototypical chordin-like cysteine-rich repeat (von Willebrand Factor type C module) from collagen IIA.
O'Leary JM, Hamilton JM, Deane CM, Valeyev NV, Sandell LJ, Downing AK
J Biol Chem 279 53857-66 (2004)
PMID: 15466413

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135854 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen alpha-1(II) chain Chain: A
Molecule details ›
Chain: A
Length: 73 amino acids
Theoretical weight: 7.98 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P02458 (Residues: 29-97; Coverage: 5%)
Gene name: COL2A1
Sequence domains: von Willebrand factor type C domain
Structure domains: Complement Module, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: semi-automated assignment and torsion angle dynamics
Expression system: Komagataella pastoris

Quick links

Citations

13 review citations

The CCN family of proteins: structure-function relationships.
Holbourn et al. (2008)
12 more

14 mentions without citation

The thrombospondins.
Adams et al. (2011)
13 more