› 1u6n

Solution NMR

Solution Structure of an Oligodeoxynucleotide Containing a Butadiene Derived N1 b-Hydroxyalkyl Adduct on Deoxyinosine in the Human N-ras Codon 61 Sequence

Released:
DOI: 10.2210/pdb1u6n/pdb
PDB entry 1u6n coloured by chain, front view.
PDB entry 1u6n coloured by chain, side view.
PDB entry 1u6n coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence.
Scholdberg TA, Merritt WK, Dean SM, Kowalcyzk A, Harris CM, Harris TM, Rizzo CJ, Lloyd RS, Stone MP
Biochemistry 44 3327-37 (2005)
PMID: 15736943

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114686 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*CP*GP*GP*AP*CP*(2BD)P*AP*GP*AP*AP*G)-3' Chain: A
Molecule details ›
Chain: A
Length: 11 nucleotides
Theoretical weight: 3.49 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.29 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 2BD 1 x 2BD

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry,simulated annealing,molecular dynamics,matrix relaxation,torsion angle dynamics
Expression system: Not provided

Quick links

Citations

3 citation in other articles

Synthesis and mutagenesis of the butadiene-derived N3 2'-deoxyuridine adducts.
Fernandes et al. (2006)
2 more