Function and Biology Details
Reactions catalysed:
N-((R)-4'-phosphopantothenoyl)-L-cysteine = pantotheine 4'-phosphate + CO(2)
CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + N-((R)-4'-phosphopantothenoyl)-L-cysteine
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coenzyme A biosynthesis bifunctional protein CoaBC
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 24.83 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA / pantothenate metabolism flavoprotein
Structure domains: CoaB-like
Length: 226 amino acids
Theoretical weight: 24.83 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P0ABQ0 (Residues: 181-406; Coverage: 56%)
Sequence domains: DNA / pantothenate metabolism flavoprotein
Structure domains: CoaB-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup:
C2
Expression system: Escherichia coli
