› 1u9k

X-ray diffraction
1.76Å resolution

Crystal Structure of Mouse Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.76

Released:
DOI: 10.2210/pdb1u9k/pdb
Model geometry
Fit model/data
PDB entry 1u9k coloured by chain, front view.
PDB entry 1u9k coloured by chain, side view.
PDB entry 1u9k coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A.
Kelker MS, Debler EW, Wilson IA
J Mol Biol 344 1175-81 (2004)
PMID: 15561137

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191628 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Triggering receptor expressed on myeloid cells 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 114 amino acids
Theoretical weight: 13.11 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9JKE2 (Residues: 21-134; Coverage: 54%)
Gene name: Trem1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ZN 3 x ZN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P212121
Unit cell:
a: 47.837Å b: 49.081Å c: 125.208Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.225 0.248
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 review citations

The TREM receptor family and signal integration.
Klesney-Tait et al. (2006)
10 more

2 mentions without citation

Analysis of domain-swapped oligomers reveals local sequence preferences and structural imprints at the linker regions and swapped interfaces.
Shingate et al. (2012)
1 more