› 1uaa

X-ray diffraction
3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114693 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
ATP-dependent DNA helicase Rep Chains: A, B
Molecule details ›
Chains: A, B
Length: 673 amino acids
Theoretical weight: 77.04 KDa
Source organism: Escherichia coli K-12
Expression system: Not provided
UniProt:
  • Canonical: P09980 (Residues: 1-673; Coverage: 100%)
Gene names: JW5604, b3778, rep
Sequence domains:
Structure domains:
DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3') Chain: C
Molecule details ›
Chain: C
Length: 16 nucleotides
Theoretical weight: 4.82 KDa
Source organism: Escherichia coli
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P43212
Unit cell:
a: 141.8Å b: 141.8Å c: 284.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.328
Expression system: Not provided

Quick links

Citations

62 review citations

Structure and mechanism of helicases and nucleic acid translocases.
Singleton et al. (2007)
61 more

27 mentions without citation

Atlas of coronavirus replicase structure.
Neuman et al. (2014)
26 more