Function and Biology Details
Reaction catalysed:
Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145199 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Uracil-DNA glycosylase
Molecule details ›
Chain: E
Length: 244 amino acids
Theoretical weight: 27.37 KDa
Source organism: Human alphaherpesvirus 1 strain 17
UniProt:
Sequence domains: Uracil DNA glycosylase superfamily
Structure domains: Uracil-DNA glycosylase-like domain
Length: 244 amino acids
Theoretical weight: 27.37 KDa
Source organism: Human alphaherpesvirus 1 strain 17
UniProt:
- Canonical:
P10186 (Residues: 91-334; Coverage: 73%)
Sequence domains: Uracil DNA glycosylase superfamily
Structure domains: Uracil-DNA glycosylase-like domain
Uracil-DNA glycosylase inhibitor
Molecule details ›
Chain: I
Length: 83 amino acids
Theoretical weight: 9.35 KDa
Source organism: Takahashivirus PBS1
UniProt:
Sequence domains: Uracil-DNA glycosylase inhibitor
Structure domains: Bacteriophage PBS2, uracil-glycosylase inhibitor
Length: 83 amino acids
Theoretical weight: 9.35 KDa
Source organism: Takahashivirus PBS1
UniProt:
- Canonical: P14739 (Residues: 2-84; Coverage: 99%)
Sequence domains: Uracil-DNA glycosylase inhibitor
Structure domains: Bacteriophage PBS2, uracil-glycosylase inhibitor
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SRS BEAMLINE PX7.2
Spacegroup:
P65
