› 1ufr

X-ray diffraction
2.6Å resolution

Crystal Structure of TT1027 from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb1ufr/pdb
PDB entry 1ufr coloured by chain, front view.
PDB entry 1ufr coloured by chain, side view.
PDB entry 1ufr coloured by chain, top view.
Source organism: Thermus thermophilus
Entry authors: Matsuura T, Sakai H, Terada T, Shirouzu M, Kuramitsu S, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178067 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bifunctional protein PyrR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 181 amino acids
Theoretical weight: 20.64 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SK65 (Residues: 1-181; Coverage: 100%)
Gene names: TTHA0783, pyrR
Sequence domains: Phosphoribosyl transferase domain
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand CL 4 x CL
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL45PX
Spacegroup: P212121
Unit cell:
a: 58.31Å b: 114.136Å c: 146.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.264 0.264 0.287
Expression system: Escherichia coli

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