› 1ug3

X-ray diffraction
2.24Å resolution

C-terminal portion of human eIF4GI

Released:
DOI: 10.2210/pdb1ug3/pdb
PDB entry 1ug3 coloured by chain, front view.
PDB entry 1ug3 coloured by chain, side view.
PDB entry 1ug3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Turning up the HEAT on translation.
Phillips SE
Structure 14 806-7 (2006)
PMID: 16698542

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 4 gamma 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 339 amino acids
Theoretical weight: 38.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q04637 (Residues: 1233-1571; Coverage: 21%)
Gene names: EIF4F, EIF4G, EIF4G1, EIF4GI
Sequence domains:
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 32-ID
Spacegroup: P21
Unit cell:
a: 78.618Å b: 50.567Å c: 99.895Å
α: 90° β: 101.59° γ: 90°
R-values:
R R work R free
0.247 0.244 0.292
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 mentions without citation

eIF4F: a retrospective.
Merrick WC. (2015)
9 more