› 1ug8

Solution NMR

NMR structure of the R3H domain from Poly(A)-specific Ribonuclease

Released:
DOI: 10.2210/pdb1ug8/pdb
PDB entry 1ug8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ug8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ug8 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Entry authors: Nagata T, Muto Y, Hayami N, Uda H, Shirouzu M, Terada T, Kigawa T, Inoue M, Yabuki T, Aoki M, Seki E, Matsuda T, Hirota H, Yoshida M, Kobayashi N, Tanaka A, Osanai T, Matsuo Y, Arakawa T, Carninci P, Kawai J, Hayashizaki Y, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Exonucleolytic cleavage of poly(A) to 5'-AMP
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186563 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Poly(A)-specific ribonuclease PARN Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 9.94 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8VDG3 (Residues: 169-242; Coverage: 12%)
Gene name: Parn
Sequence domains: R3H domain
Structure domains: R3H-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Not provided

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