1uix

X-ray diffraction
1.8Å resolution

Coiled-coil structure of the RhoA-binding domain in Rho-kinase

Released:
Source organism: Bos taurus

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-173301 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho-associated protein kinase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 71 amino acids
Theoretical weight: 8.06 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q28021 (Residues: 979-1047; Coverage: 5%)
Gene name: ROCK2
Sequence domains: Rho Binding
Structure domains: Single helix bin

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-18B
Spacegroup: C2
Unit cell:
a: 148Å b: 26.1Å c: 39.6Å
α: 90° β: 90.4° γ: 90°
R-values:
R R work R free
0.219 0.193 0.236
Expression system: Escherichia coli