› 1uld

X-ray diffraction
2.1Å resolution

CGL2 in complex with blood group H type II

Released:
DOI: 10.2210/pdb1uld/pdb
PDB entry 1uld coloured by chain, front view.
PDB entry 1uld coloured by chain, side view.
PDB entry 1uld coloured by chain, top view.
Source organism: Coprinopsis cinerea
Primary publication:
Structure and functional analysis of the fungal galectin CGL2.
Walser PJ, Haebel PW, Künzler M, Sargent D, Kües U, Aebi M, Ban N
Structure 12 689-702 (2004)
PMID: 15062091

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192854 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 150 amino acids
Theoretical weight: 16.77 KDa
Source organism: Coprinopsis cinerea
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q9P4R8 (Residues: 1-150; Coverage: 100%)
Gene name: Cgl2
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3112
Unit cell:
a: 113.613Å b: 113.613Å c: 122.329Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.218 0.247
Expression system: Saccharomyces cerevisiae

Quick links

Citations

11 review citations

Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates.
Vasta et al. (2004)
10 more

3 mentions without citation

Mushroom lectins: specificity, structure and bioactivity relevant to human disease.
Hassan et al. (2015)
2 more