› 1ulf

X-ray diffraction
2.36Å resolution

CGL2 in complex with Blood Group A tetrasaccharide

Released:
DOI: 10.2210/pdb1ulf/pdb
PDB entry 1ulf coloured by chain, front view.
PDB entry 1ulf coloured by chain, side view.
PDB entry 1ulf coloured by chain, top view.
Source organism: Coprinopsis cinerea
Primary publication:
Structure and functional analysis of the fungal galectin CGL2.
Walser PJ, Haebel PW, Künzler M, Sargent D, Kües U, Aebi M, Ban N
Structure 12 689-702 (2004)
PMID: 15062091

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192855 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 150 amino acids
Theoretical weight: 16.77 KDa
Source organism: Coprinopsis cinerea
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q9P4R8 (Residues: 1-150; Coverage: 100%)
Gene name: Cgl2
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL, FUC, A2G
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3221
Unit cell:
a: 61.409Å b: 61.409Å c: 194.233Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.209 0.247
Expression system: Saccharomyces cerevisiae

Quick links

Citations

12 review citations

Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates.
Vasta et al. (2004)
11 more

6 mentions without citation

The Structural Biology of Galectin-Ligand Recognition: Current Advances in Modeling Tools, Protein Engineering, and Inhibitor Design.
Modenutti et al. (2019)
5 more