Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- DNA clamp superfamily
- DNA polymerase III, beta sliding clamp
- DNA polymerase, Y-family, little finger domain superfamily
- DNA polymerase, Y-family, little finger domain
- DNA polymerase III, beta sliding clamp, C-terminal
- DNA polymerase III, beta sliding clamp, central
- DNA polymerase III, beta sliding clamp, N-terminal
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141849 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Beta sliding clamp
Molecule details ›
Chains: A, B
Length: 366 amino acids
Theoretical weight: 40.63 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 366 amino acids
Theoretical weight: 40.63 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P0A988 (Residues: 1-366; Coverage: 100%)
Sequence domains:
- DNA polymerase III beta subunit, N-terminal domain
- DNA polymerase III beta subunit, central domain
- DNA polymerase III beta subunit, C-terminal domain
DNA polymerase IV
Molecule details ›
Chains: C, D
Length: 115 amino acids
Theoretical weight: 13.56 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: impB/mucB/samB family C-terminal domain
Structure domains: DNA polymerase, Y-family, little finger domain
Length: 115 amino acids
Theoretical weight: 13.56 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: Q47155 (Residues: 243-351; Coverage: 31%)
Sequence domains: impB/mucB/samB family C-terminal domain
Structure domains: DNA polymerase, Y-family, little finger domain
