› 1uns

X-ray diffraction
2Å resolution

IDENTIFICATION OF A SECONDARY ZINC-BINDING SITE IN STAPHYLOCOCCAL ENTEROTOXIN C2: IMPLICATIONS FOR SUPERANTIGEN RECOGNITION

Released:
DOI: 10.2210/pdb1uns/pdb
PDB entry 1uns coloured by chain, front view.
PDB entry 1uns coloured by chain, side view.
PDB entry 1uns coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition.
Papageorgiou AC, Baker MD, McLeod JD, Goda SK, Manzotti CN, Sansom DM, Tranter HS, Acharya KR
J Biol Chem 279 1297-303 (2004)
PMID: 14559915

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152677 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enterotoxin type C-2 Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 27.62 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: P34071 (Residues: 28-266; Coverage: 100%)
Gene name: entC2
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: P212121
Unit cell:
a: 42.5Å b: 44.54Å c: 131.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.225

Quick links

Citations

2 review citations

Structural basis of metal hypersensitivity.
Wang et al. (2013)
1 more

2 mentions without citation

Relating destabilizing regions to known functional sites in proteins.
Dessailly et al. (2007)
1 more