› 1uuh

X-ray diffraction
2.2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147592 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD44 antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 159 amino acids
Theoretical weight: 17.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P16070 (Residues: 20-178; Coverage: 22%)
Gene names: CD44, LHR, MDU2, MDU3, MIC4
Sequence domains: Extracellular link domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 48.881Å b: 77.266Å c: 87.668Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.186 0.249
Expression system: Escherichia coli BL21

Quick links

Citations

32 review citations

Hyaluronan as an immune regulator in human diseases.
Jiang et al. (2011)
31 more

33 mentions without citation

Three-dimensional structural aspects of protein-polysaccharide interactions.
Nagae et al. (2014)
32 more