› 1uv0

X-ray diffraction
1.78Å resolution

Pancreatitis-associated protein 1 from human

Released:
DOI: 10.2210/pdb1uv0/pdb
PDB entry 1uv0 coloured by chain, front view.
PDB entry 1uv0 coloured by chain, side view.
PDB entry 1uv0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallization and preliminary crystallographic study of HIP/PAP, a human C-lectin overexpressed in primary liver cancers.
Abergel C, Chenivesse S, Stinnakre MG, Guasco S, Bréchot C, Claverie JM, Devinoy E, Christa L
Acta Crystallogr D Biol Crystallogr 55 1487-9 (1999)
PMID: 10417404

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170294 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regenerating islet-derived protein 3-alpha Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 16.58 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: Q06141 (Residues: 27-175; Coverage: 100%)
Gene names: HIP, PAP, PAP1, REG3A
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

1 bound ligand:
Ligand ZN 3 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW21B
Spacegroup: P212121
Unit cell:
a: 30.73Å b: 49.35Å c: 92.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.188 0.244
Expression system: Mus musculus

Quick links

Citations

1 review citation

The C-type lectin-like domain superfamily.
Zelensky et al. (2005)
5 other articles

7 mentions without citation

Antibacterial membrane attack by a pore-forming intestinal C-type lectin.
Mukherjee et al. (2014)
6 more