› 1uvx

X-ray diffraction
2.45Å resolution

Heme-ligand tunneling on group I truncated hemoglobins

Released:
DOI: 10.2210/pdb1uvx/pdb
PDB entry 1uvx coloured by chain, front view.
PDB entry 1uvx coloured by chain, side view.
PDB entry 1uvx coloured by chain, top view.
Source organism: Chlamydomonas moewusii
Primary publication:
Heme-ligand tunneling in group I truncated hemoglobins.
Milani M, Pesce A, Ouellet Y, Dewilde S, Friedman J, Ascenzi P, Guertin M, Bolognesi M
J Biol Chem 279 21520-5 (2004)
PMID: 15016811

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170690 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Group 1 truncated hemoglobin LI637 Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.32 KDa
Source organism: Chlamydomonas moewusii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08753 (Residues: 44-164; Coverage: 74%)
Gene name: LI637
Sequence domains: Bacterial-like globin
Structure domains: Globins

Ligands and Environments

3 bound ligands:
Ligand HEM 1 x HEM
Ligand CYN 1 x CYN
Ligand XE 4 x XE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 34.499Å b: 52.932Å c: 66.993Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.21 0.268
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Structure and regulation of soluble guanylate cyclase.
Derbyshire et al. (2012)
7 more

1 mention without citation

Evolutionary and Functional Relationships in the Truncated Hemoglobin Family.
Bustamante et al. (2016)