› 1ux4

X-ray diffraction
3.3Å resolution

Crystal structures of a Formin Homology-2 domain reveal a tethered-dimer architecture

Released:
DOI: 10.2210/pdb1ux4/pdb
PDB entry 1ux4 coloured by chain, front view.
PDB entry 1ux4 coloured by chain, side view.
PDB entry 1ux4 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture.
Xu Y, Moseley JB, Sagot I, Poy F, Pellman D, Goode BL, Eck MJ
Cell 116 711-23 (2004)
PMID: 15006353

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154463 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein BNI1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 410 amino acids
Theoretical weight: 47.21 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P41832 (Residues: 1352-1765; Coverage: 21%)
Gene names: BNI1, N0646, PPF3, SHE5, YNL271C
Sequence domains: Formin Homology 2 Domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 8-BM
Spacegroup: C2
Unit cell:
a: 98.1Å b: 172.2Å c: 120.6Å
α: 90° β: 112.3° γ: 90°
R-values:
R R work R free
0.234 0.234 0.289
Expression system: Escherichia coli

Quick links

Citations

50 review citations

Regulation of actin filament assembly by Arp2/3 complex and formins.
Pollard TD. (2007)
49 more

1 mention without citation

FHODs: Nuclear tethered formins for nuclear mechanotransduction.
Antoku et al. (2023)