› 1uyb

Solution NMR

THE SOLUTION STRUCTURE OF THE B-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES

Released:
DOI: 10.2210/pdb1uyb/pdb
PDB entry 1uyb coloured by chain, ensemble of 10 models, front view.
PDB entry 1uyb coloured by chain, ensemble of 10 models, side view.
PDB entry 1uyb coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers.
Marx UC, Klodt J, Meyer M, Gerlach H, Rösch P, Forssmann WG, Adermann K
J Pept Res 52 229-40 (1998)
PMID: 9774236

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uroguanylin Chain: A
Molecule details ›
Chain: A
Length: 16 amino acids
Theoretical weight: 1.67 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q16661 (Residues: 97-112; Coverage: 19%)
Gene name: GUCA2B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: SIMULATED ANNEALING, RESTRAINED MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

7 review citations

Heat-stable enterotoxin of enterotoxigenic Escherichia coli as a vaccine target.
Taxt et al. (2010)
6 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)