› 1v0j

X-ray diffraction
2.25Å resolution

Function and Biology Details

Reaction catalysed: 
UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161655 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UDP-galactopyranose mutase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 399 amino acids
Theoretical weight: 45.87 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WIQ1 (Residues: 1-399; Coverage: 100%)
Gene names: Rv3809c, glf
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments


Cofactor: Ligand FAD 4 x FAD
1 bound ligand:
Ligand BCN 1 x BCN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21212
Unit cell:
a: 137.601Å b: 153.733Å c: 137.688Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.225 0.266
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

Chemistry and biology of galactofuranose-containing polysaccharides.
Richards et al. (2009)
11 more

8 mentions without citation

Structure, mechanism, and dynamics of UDP-galactopyranose mutase.
Tanner et al. (2014)
7 more