› 1v6p

X-ray diffraction
0.87Å resolution

Crystal structure of Cobrotoxin

Released:
DOI: 10.2210/pdb1v6p/pdb
PDB entry 1v6p coloured by chain, front view.
PDB entry 1v6p coloured by chain, side view.
PDB entry 1v6p coloured by chain, top view.
Source organism: Naja atra
Primary publication:
The atomic resolution crystal structure of atratoxin determined by single wavelength anomalous diffraction phasing.
Lou X, Liu Q, Tu X, Wang J, Teng M, Niu L, Schuller DJ, Huang Q, Hao Q
J Biol Chem 279 39094-104 (2004)
PMID: 15252034

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cobrotoxin Chains: A, B
Molecule details ›
Chains: A, B
Length: 62 amino acids
Theoretical weight: 6.97 KDa
Source organism: Naja atra
UniProt:
  • Canonical: P60770 (Residues: 22-83; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

4 bound ligands:
Ligand CU 12 x CU
Ligand CL 1 x CL
Ligand NA 2 x NA
Ligand EOH 2 x EOH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: C2221
Unit cell:
a: 46.808Å b: 47.287Å c: 90.018Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.12 0.12 0.153

Quick links

Citations

2 review citations

Multifunctional nanoparticles for brain tumor imaging and therapy.
Cheng et al. (2014)
1 more

7 mentions without citation

Identification of hot-spot residues in protein-protein interactions by computational docking.
Grosdidier et al. (2008)
6 more