› 1v98

X-ray diffraction
1.82Å resolution

Crystal Structure Analysis of Thioredoxin from Thermus thermophilus

Released:
DOI: 10.2210/pdb1v98/pdb
PDB entry 1v98 coloured by chain, front view.
PDB entry 1v98 coloured by chain, side view.
PDB entry 1v98 coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Rehse PH, Tahirov TH, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177942 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 15.18 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SI93 (Residues: 1-140; Coverage: 100%)
Gene name: TTHA1481
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: C2
Unit cell:
a: 40.91Å b: 95.441Å c: 56.683Å
α: 90° β: 91.41° γ: 90°
R-values:
R R work R free
0.195 0.195 0.236
Expression system: Escherichia coli BL21(DE3)

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