Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 300-mer (preferred)
Assembly name:
Capsid protein VP2 and peptide (preferred)
PDBe Complex ID:
PDB-CPX-136728 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Capsid protein VP1
Molecule details ›
Chain: 1
Length: 300 amino acids
Theoretical weight: 33.52 KDa
Source organism: Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B)
UniProt:
Structure domains: Jelly Rolls
Length: 300 amino acids
Theoretical weight: 33.52 KDa
Source organism: Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B)
UniProt:
- Canonical:
P03302 (Residues: 579-878; Coverage: 14%)
Structure domains: Jelly Rolls
Capsid protein VP2
Capsid protein VP3
Capsid protein VP4
