› 1vbj

X-ray diffraction
2.1Å resolution

The crystal structure of prostaglandin F synthase from Trypanosoma brucei

Released:
DOI: 10.2210/pdb1vbj/pdb
PDB entry 1vbj coloured by chain, front view.
PDB entry 1vbj coloured by chain, side view.
PDB entry 1vbj coloured by chain, top view.
Source organism: Trypanosoma brucei
Entry author: Inoue T

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190433 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
9,11-endoperoxide prostaglandin H2 reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 281 amino acids
Theoretical weight: 31.55 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GV41 (Residues: 1-276; Coverage: 100%)
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain

Ligands and Environments

2 bound ligands:
Ligand NAP 2 x NAP
Ligand CIT 2 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL12B2
Spacegroup: P41212
Unit cell:
a: 113.212Å b: 113.212Å c: 136.269Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 0.26
Expression system: Escherichia coli

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