› 1vch

X-ray diffraction
1.94Å resolution

Crystal Structure of a Phosphoribosyltransferase-related protein from Thermus thermophilus

Released:
DOI: 10.2210/pdb1vch/pdb
PDB entry 1vch coloured by chain, front view.
PDB entry 1vch coloured by chain, side view.
PDB entry 1vch coloured by chain, top view.
Source organism: Thermus thermophilus
Entry authors: Rehse PH, Tahirov TH, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo decamer
Assembly name:
PDBe Complex ID:
PDB-CPX-177912 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenine phosphoribosyltransferase Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 175 amino acids
Theoretical weight: 19.36 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SHW7 (Residues: 1-175; Coverage: 100%)
Gene name: TTHA1613
Structure domains: Rossmann fold

Ligands and Environments

3 bound ligands:
Ligand ACY 4 x ACY
Ligand CL 5 x CL
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1, null
Spacegroup: C2
Unit cell:
a: 167.419Å b: 61.405Å c: 102.389Å
α: 90° β: 93.97° γ: 90°
R-values:
R R work R free
0.232 0.232 0.259
Expression system: Escherichia coli BL21(DE3)

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