› 1ve5

X-ray diffraction
2.15Å resolution

Crystal Structure of T.th. HB8 Threonine deaminase

Released:
DOI: 10.2210/pdb1ve5/pdb
PDB entry 1ve5 coloured by chain, front view.
PDB entry 1ve5 coloured by chain, side view.
PDB entry 1ve5 coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Goto M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(1a) L-threonine = 2-aminobut-2-enoate + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178179 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tryptophan synthase beta chain-like PALP domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 311 amino acids
Theoretical weight: 32.82 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SLL4 (Residues: 1-311; Coverage: 100%)
Gene name: TTHA0279
Sequence domains: Pyridoxal-phosphate dependent enzyme
Structure domains: Rossmann fold

Ligands and Environments


Cofactor: Ligand PLP 4 x PLP
1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P21
Unit cell:
a: 53.59Å b: 158.19Å c: 80.3Å
α: 90° β: 108.52° γ: 90°
R-values:
R R work R free
0.202 0.202 0.245
Expression system: Escherichia coli

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