› 1vhp

Solution NMR

VH-P8, NMR

Released:
DOI: 10.2210/pdb1vhp/pdb
PDB entry 1vhp coloured by chain, ensemble of 20 models, front view.
PDB entry 1vhp coloured by chain, ensemble of 20 models, side view.
PDB entry 1vhp coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Rearrangement of the former VL interface in the solution structure of a camelised, single antibody VH domain.
Riechmann L
J Mol Biol 259 957-69 (1996)
PMID: 8683598

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213104 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
VH-P8 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 12.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Domain antibodies: proteins for therapy.
Holt et al. (2003)
13 more

5 mentions without citation

Cell penetrable humanized-VH/V(H)H that inhibit RNA dependent RNA polymerase (NS5B) of HCV.
Thueng-in et al. (2012)
4 more