› 1vin

X-ray diffraction
2Å resolution

BOVINE CYCLIN A3

Released:
DOI: 10.2210/pdb1vin/pdb
PDB entry 1vin coloured by chain, front view.
PDB entry 1vin coloured by chain, side view.
PDB entry 1vin coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The crystal structure of cyclin A.
Brown NR, Noble ME, Endicott JA, Garman EF, Wakatsuki S, Mitchell E, Rasmussen B, Hunt T, Johnson LN
Structure 3 1235-47 (1995)
PMID: 8591034

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151695 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclin-A2 Chain: A
Molecule details ›
Chain: A
Length: 268 amino acids
Theoretical weight: 30.83 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P30274 (Residues: 169-430; Coverage: 61%)
Gene name: CCNA2
Sequence domains:
Structure domains: Cyclin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX7.2
Spacegroup: P212121
Unit cell:
a: 52.7Å b: 60.9Å c: 83.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.216 0.299
Expression system: Escherichia coli

Quick links

Citations

31 review citations

Cyclin-dependent kinases: engines, clocks, and microprocessors.
Morgan DO. (1997)
30 more

11 mentions without citation

Structural insights into the functional diversity of the CDK-cyclin family.
Wood et al. (2018)
10 more